Article
Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as wel as for reverse transcription.
Nature - 5 Apr 1990
Hirsch R C, Lavine J E, Chang L J, Varmus H E, Ganem D
Abstract excerpt
All reactions involving reverse transcription of RNA are segregated from the cytosol within a subviral particle or capsid composed of the major capsid protein, the polymerase and the RNA template. A key step in the formation of these particles is the selective encapsidation of the RNA template. Although an important general feature of the reverse transcription pathway, encapsidation has been carefully studied...
Topics
- Amino Acid Sequence
- Codon
- DNA-Directed RNA Polymerases
- Genes, Viral
- Hepatitis B Virus, Duck
- Molecular Sequence Data
- Mutation
- RNA, Viral
- RNA-Directed DNA Polymerase
- Transcription, Genetic
- Transfection
