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Article

Sequence-specific interactions in the RNA-binding domain of Escherichia coli transcription termination factor Rho.

The Journal of biological chemistry - 3 Nov 2006

Hitchens T Kevin, Zhan Yiping, Richardson Lislott V, Richardson John P, Rule Gordon S

Abstract excerpt

Rho factor is an essential protein that causes termination of transcription in a wide variety of bacteria by an RNA-dependent helicase activity. Rho is activated by transcripts that contain a high proportion of cytidine residues. The interaction between Rho and two adjacent cytidine residues within the bound RNA has been identified by previous crystallographic studies (Skordalakes, E., and Berger, J. M. (2003)...

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Source

Identifiers

PMID: 16908525
DOI: 10.1074/jbc.M605312200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Sequence-specific interactions in the RNA-binding domain of Escherichia coli transcription termination factor Rho.PMID 16908525Read ↗

Analysis of E. coli rho factor: mutations affecting secondary-site interactions.Semantic proximity Read ↗

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Mutations in the rho transcription termination factor that affect RNA tracking.Semantic proximity Read ↗

The bicyclomycin sensitivities of 38 bicyclomycin-resistant mutants of transcription termination protein rho and the location of their mutations support a structural model of rho based on the F(1) ATPase.Semantic proximity Read ↗

Mutagenesis-based evidence for an asymmetric configuration of the ring-shaped transcription termination factor Rho.Semantic proximity Read ↗

Amino acid substitutions in the two largest subunits of Escherichia coli RNA polymerase that suppress a defective Rho termination factor affect different parts of the transcription complex.Semantic proximity Read ↗

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Residues in the RNP1-like sequence motif of Rho protein are involved in RNA-binding affinity and discrimination.Semantic proximity Read ↗

Redundancy of primary RNA-binding functions of the bacterial transcription terminator Rho.Semantic proximity Read ↗

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