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Article

Mouse retinal progenitor cell (RPC) cocultivation with retinal pigment epithelial cell culture affects features of RPC differentiation.

Biochemistry. Biokhimiia - 1 Jul 2006

Kholodenko I V, Buzdin A A, Kholodenko R V, Baibikova J A, Sorokin V F, Yarygin V N, Sverdlov E D

Abstract excerpt

We provide evidence that coculturing of retinal progenitor cells (RPC) with retinal pigment epithelial cells significantly biases the standard in vitro RPC differentiation patterns. In particular, in cocultivation experiments RPCs lost the ability to differentiate spontaneously and displayed approximately 2.1-2.4-fold increase in immunoreactivity to the neural stem cell marker nestin and approximately...

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PMID: 16903831
DOI: 10.1134/s0006297906070091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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