Article
Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate.
Investigative ophthalmology & visual science - 1 Jan 2007
Canola Kriss, Angénieux Brigitte, Tekaya Meriem, Quiambao Alexander, Naash Muna I, Munier Francis L, Schorderet Daniel F, Arsenijevic Yvan
Abstract excerpt
PURPOSE: To characterize the potential of newborn retinal stem cells (RSCs) isolated from the radial glia population to integrate the retina, this study was conducted to investigate the fate of in vitro expanded RSCs transplanted into retinas devoid of photoreceptors (adult rd1 and old VPP mice and rhodopsin-mutated transgenic mice) or partially degenerated retina (adult VPP mice) retinas. METHODS: Populations of...
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