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Article

Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1.

Stem cells (Dayton, Ohio) - 1 Dec 2008

Gamm David M, Wright Lynda S, Capowski Elizabeth E, Shearer Rebecca L, Meyer Jason S, Kim Hyun-Jung, Schneider Bernard L, Melvan John Nicholas, Svendsen Clive N

Abstract excerpt

During development of the central nervous system, stem and progenitor cell proliferation and differentiation are controlled by complex inter- and intracellular interactions that orchestrate the precise spatiotemporal production of particular cell types. Within the embryonic retina, progenitor cells are located adjacent to the retinal pigment epithelium (RPE), which differentiates prior to the neurosensory retina...

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Source

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Identifiers

PMID: 18802035
DOI: 10.1634/stemcells.2008-0300
PMCID: PMC3127245

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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