Article
Molecular analysis of colonic transformation in the ileum after total colectomy in rats.
Surgery - 1 Jul 2006
Fukushima Kouhei, Haneda Sho, Takahashi Ken-Ichi, Ogawa Hitoshi, Watanabe Kazuhiro, Funayama Yuji, Shibata Chikashi, Sasaki Iwao
Abstract excerpt
BACKGROUND: Colonic transformation is thought to be a phenotypic alteration in the ileum after total colectomy (TC) but has not been well addressed at the molecular level. We previously demonstrated roles of aldosterone in enhancement of ileal sodium absorption after TC. However, the significance of aldosterone in intestinal adaptation has been unknown. METHODS: Rat epithelial gene expression was compared between...
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