Article
Haptoglobin gene promoter polymorphism and haplotypes are unique in different populations.
Human biology - 1 Feb 2006
Teye Kwesi, Soejima Mikiko, Quaye Isaac K E, Pang Hao, Tsuneoka Makoto, Koda Yoshiro, Kimura Hiroshi
Abstract excerpt
We investigated the distribution of haptoglobin (HP) alleles and haplotypes among Africans (Ghanaians), Europeans (from South Africa), and Chinese. HP*1F was present only in Africans and Europeans, whereas HP*del was unique to Chinese. Six base substitutions at the promoter region were population specific. Only 3 out of 18 haplotypes were shared among the populations. A probable application of HP in human...
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