Article
The melanocortin circuit in obese and lean strains of chicks.
The Journal of endocrinology - 1 Aug 2006
Hen Gideon, Yosefi Sara, Simchaev Victoria, Shinder Dmitry, Hruby Victor J, Friedman-Einat Miriam
Abstract excerpt
Agonists of membranal melanocortin 3 and 4 receptors (MC3/4Rs) are known to take part in the complex control mechanism of energy balance. In this study, we compared the physiological response to an exogenous MC3/4R agonist and the hypothalamic expression of proopic melanocortin (POMC) gene, encoding few MC3/4R ligands, between broiler and layer chicken strains. These strains, representing the two most prominent...
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