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Article

Cell and animal models of mtDNA biology: progress and prospects.

American journal of physiology. Cell physiology - 1 Feb 2007

Khan Shaharyar M, Smigrodzki Rafal M, Swerdlow Russell H

Abstract excerpt

The past two decades have witnessed an evolving understanding of the mitochondrial genome's (mtDNA) role in basic biology and disease. From the recognition that mutations in mtDNA can be responsible for human disease to recent efforts showing that mtDNA mutations accumulate over time and may be responsible for some phenotypes of aging, the field of mitochondrial genetics has greatly benefited from the creation of...

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PMID: 16899549
DOI: 10.1152/ajpcell.00224.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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