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Article

Prion protein gene M129 allele is a risk factor for Alzheimer's disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2006

Gacia M, Safranow K, Styczyńska M, Jakubowska K, Pepłońska B, Chodakowska-Zebrowska M, Przekop I, Słowik A, Golańska E, Hułas-Bigoszewska K, Chlubek D, Religa D, Zekanowski C, Barcikowska M

Abstract excerpt

Prion protein gene polymorphism M129V represents a known risk factor for Creutzfeldt-Jakob disease. Recently, the meta-analysis revealed that homozygosity at codon 129 is connected with increased risk of Alzheimer's disease (AD). To determine whether M129V polymorphism is a risk factor for AD we analyzed a group of early-onset, and late-onset Polish AD patients. We observed that in LOAD patients there is a...

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Identifiers

PMID: 16897605
DOI: 10.1007/s00702-006-0540-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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