Article
A molecular approach to the identification of cytotoxic T-lymphocyte epitopes within equine herpesvirus 1.
The Journal of general virology - 1 Sept 2006
Kydd Julia H, Davis-Poynter N J, Birch J, Hannant D, Minke J, Audonnet J-C, Antczak D F, Ellis Shirley A
Abstract excerpt
Equine herpesvirus 1 (EHV-1) causes respiratory and neurological disease and abortion in horses. Animals with high frequencies of cytotoxic T lymphocytes (CTL) show reduced severity of respiratory disease and frequency of abortion, probably by CTL-mediated control of cell-associated viraemia. This study aimed to identify CTL epitopes restricted by selected major histocompatibility complex (MHC) class I alleles...
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