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Article

A645G (Lys216Glu) polymorphism of the bactericidal/permeability-increasing protein gene in periodontal disease.

International journal of immunogenetics - 1 Aug 2006

Glas J, Török H-P, Tonenchi L, Hamann S, Malachova O, Euba A, Folwaczny C, Folwaczny M

Abstract excerpt

Bactericidal/permeability-increasing protein (BPI) is a member of the pattern recognition receptors of the innate immune system and recognizes lipopolysaccharides (LPS), a bacterial component belonging to the pathogen-associated molecular patterns (PAMPs). BPI mediates the neutralization of LPS and increases the phagocytosis and cytotoxicity against bacteria. Recently, the functionally effective polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16893388
DOI: 10.1111/j.1744-313X.2006.00608.x

Genes

BPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A645G (Lys216Glu) polymorphism of the bactericidal/permeability-increasing protein gene in periodontal disease.PMID 16893388Read ↗

A polymorphism of the bactericidal/permeability increasing protein (BPI) gene is associated with Crohn's disease.Semantic proximity Read ↗

Association between bactericidal/permeability increasing protein (BPI) gene polymorphism (Lys216Glu) and inflammatory bowel disease.Semantic proximity Read ↗

A Polymorphism of Bactericidal/Permeability-Increasing Protein Affects Its Neutralization Efficiency towards Lipopolysaccharide.Semantic proximity Read ↗

Bactericidal/permeability increasing protein gene polymorphism and inflammatory bowel diseases: meta-analysis of five case-control studies.Semantic proximity Read ↗

Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease.Semantic proximity Read ↗

Polymorphisms in the lipopolysaccharide-binding protein and bactericidal/permeability-increasing protein in patients with myocardial infarction.Semantic proximity Read ↗

Association of the FcγRIIB-nt645+25A/G polymorphism with the expression level of the FcγRIIb receptor, the antibody response to Porphyromonas gingivalis and the severity of periodontitis.Semantic proximity Read ↗

Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling.Semantic proximity Read ↗

Association study of Wegener granulomatosis and the functionally relevant A645G polymorphism in the bactericidal/permeability increasing protein (BPI) gene.Semantic proximity Read ↗

Gene variants of the bactericidal/permeability increasing protein and lipopolysaccharide binding protein in sepsis patients: gender-specific genetic predisposition to sepsis.Semantic proximity Read ↗

Relevance of IgG receptor IIIb (CD16) polymorphism to handling of Porphyromonas gingivalis: implications for the pathogenesis of adult periodontitis.Semantic proximity Read ↗

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