Article
Association between bactericidal/permeability increasing protein (BPI) gene polymorphism (Lys216Glu) and inflammatory bowel disease.
Journal of Crohn's & colitis - 1 Feb 2011
Akin Hakan, Tahan Gülgün, Türe Filiz, Eren Fatih, Atuğ Ozlen, Tahan Veysel, Hamzaoğlu Ismail, Imeryüz Neşe, Tözün Nurdan, Hamzaoglu Hulya Over
Abstract excerpt
BACKGROUND: Increasing evidence suggests that innate immune system may have a key role in the pathogenesis of the inflammatory bowel disease (IBD). Bactericidal/permeability increasing protein (BPI) has an important role in the recognition and neutralization of gram-negative bacteria by host innate immune system. The polymorphism on BPI gene called Lys216Glu is on the suspected list of IBD pathogenesis. METHODS:...
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