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Article

ADAM 12 as a first‐trimester maternal serum marker in screening for Down syndrome

7 Aug 2006

Abstract excerpt

BACKGROUND: A Disintegrin And Metalloprotease 12 (ADAM 12) is a glycoprotein synthesised by placenta and it has been shown to be a potential first-trimester maternal serum marker for Down syndrome (DS) in two small series. Here we analyse further, the potential of ADAM 12 as a marker for DS in a large collection of first-trimester serum samples. MATERIALS AND METHODS: The concentration of ADAM 12 was determined...

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Identifiers

PMID: 16892462
DOI: 10.1002/pd.1540

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