Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The history of the second‐trimester sonographic markers for detecting fetal Down syndrome, and their current role in obstetric practice

22 Jun 2010

Abstract excerpt

This review summarizes the development, history and use of second-trimester sonographic markers for the detection of fetal Down syndrome over three decades. Starting with the nuchal fold thickening in 1985 and culminating in the genetic sonogram in the 1990 s. The combination of second-trimester serum screening with the ultrasound markers improved the detection rate of affected fetuses but also allowed patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fetal and Pediatric Neurological Disorders
Share to Parvovirus B19 Infection Studies
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20572106
DOI: 10.1002/pd.2531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The history of the second‐trimester sonographic markers for detecting fetal Down syndrome, and their current role in obstetric practicePMID 20572106Read ↗

Second trimester ultrasound screening for chromosomal abnormalitiesSemantic proximity Read ↗

First trimester fetal nuchal translucencySemantic proximity Read ↗

ACOG Practice Bulletin No. 77: Screening for Fetal Chromosomal AbnormalitiesSemantic proximity Read ↗

First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screeningSemantic proximity Read ↗

Use of the genetic sonogram in the United States in 2001 and 2007.Semantic proximity Read ↗

Prenatal screening for trisomy 21 (Down syndrome) using first- and second-trimester biochemistry and nuchal translucency: A technical standard of the American College of Medical Genetics and Genomics (ACMG)Semantic proximity Read ↗

First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screeningSemantic proximity Read ↗

First trimester combined screening for fetal aneuploidies enhanced with additional ultrasound markers: an 8-year prospective study.Semantic proximity Read ↗

Ultrasonographic fetal soft markers in a low‐risk population: prevalence, association with trisomies and invasive testsSemantic proximity Read ↗

Advances in prenatal screening for Down syndrome: I. General principles and second trimester testingSemantic proximity Read ↗

The second trimester genetic sonogramSemantic proximity Read ↗

Role of Second-Trimester Genetic Sonography After Down Syndrome ScreeningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.