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Article

Proteomics and Down syndrome screening: a validation study

8 Sept 2010

Abstract excerpt

OBJECTIVE: In a previous discovery study, we identified seven potential screening markers for Down syndrome (DS). Here, we report on an extended study to validate the discriminative potential of these markers. METHODS: Concentrations of the seven analytes were measured using bead-based multiplexed immunoassays in maternal serum from 27 DS pregnancies and 27 matched controls. Control samples were matched to the...

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Share to Down syndrome and intellectual disability research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20827711
DOI: 10.1002/pd.2606

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