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Article

PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway.

Gastroenterology - 1 Aug 2006

Varnat Frédéric, Heggeler Béatrice Bordier-Ten, Grisel Philippe, Boucard Nathalie, Corthésy-Theulaz Irène, Wahli Walter, Desvergne Béatrice

Abstract excerpt

BACKGROUND & AIMS: All 4 differentiated epithelial cell types found in the intestinal epithelium derive from the intestinal epithelial stem cells present in the crypt unit, in a process whose molecular clues are intensely scrutinized. Peroxisome proliferator-activated receptor beta (PPARbeta) is a nuclear hormone receptor activated by fatty acids and is highly expressed in the digestive tract. However, its...

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Identifiers

PMID: 16890607
DOI: 10.1053/j.gastro.2006.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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