Co-ordinate action of bacterial adhesins and human carcinoembryonic antigen receptors in enhanced cellular invasion by capsulate serum resistant Neisseria meningitidis.

Abstract excerpt

Neisseria meningitidis (Nm) is a human specific opportunistic pathogen that occasionally penetrates mucosal barriers via the action of adhesins and invasins and evades host immune mechanisms during further dissemination via capsule expression. From in vitro studies, the primary adhesion of capsulate bacteria is believed to be mediated by polymeric pili, followed by invasion via outer membrane adhesins such as Opa...

Topics

• Adhesins, Bacterial
• Animals
• Antigens, CD
• Bacterial Adhesion
• Bacterial Capsules
• Bacterial Outer Membrane Proteins
• Blood Bactericidal Activity
• CHO Cells
• Cell Adhesion Molecules
• Cell Line
• Cell Line, Tumor
• Cricetinae
• Cricetulus