Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells.

Infection and immunity - 1 Nov 2009

Youssef Abdel-Rahman, van der Flier Michiel, Estevão Silvia, Hartwig Nico G, van der Ley Peter, Virji Mumtaz

Abstract excerpt

T cells may interact with a number of bacterial surface antigens, an encounter which has the potential to downmodulate host immune responses. Neisseria meningitidis, a human colonizer and an agent of septicemia and meningitis, expresses Opa proteins which interact with the CEACAM1 receptor expres...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Bacterial
Share to Bacterial Outer Membrane Proteins
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules

Share to Fluorescent Antibody Technique

Share to Meningococcal Infections

Share to Neisseria gonorrhoeae

Share to Neisseria meningitidis

Source

Open in PubMed Open full text

Identifiers

PMID: 19720754
DOI: 10.1128/IAI.00355-09
PMCID: PMC2772550

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19720754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells.PMID 19720754Read ↗

Opa proteins and CEACAMs: pathways of immune engagement for pathogenicNeisseriaSemantic proximity Read ↗

Neisserial Opa Protein–CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and PathogenesisSemantic proximity Read ↗

Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells.Semantic proximity Read ↗

In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.Semantic proximity Read ↗

Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections.Semantic proximity Read ↗

Expression of pathogen-like Opa adhesins in commensal Neisseria: genetic and functional analysisSemantic proximity Read ↗

Co-ordinate action of bacterial adhesins and human carcinoembryonic antigen receptors in enhanced cellular invasion by capsulate serum resistant Neisseria meningitidis.Semantic proximity Read ↗

Molecular analysis of neisserial Opa protein interactions with the CEA family of receptors: identification of determinants contributing to the differential specificities of bindingSemantic proximity Read ↗

Expression of Opacity Proteins Interferes with the Transmigration of Neisseria gonorrhoeae across Polarized Epithelial CellsSemantic proximity Read ↗

Carcinoembryonic Antigen Family Receptor Recognition by Gonococcal Opa Proteins Requires Distinct Combinations of Hypervariable Opa Protein DomainsSemantic proximity Read ↗

Neisseria meningitidis producing the Opc adhesin binds epithelial cell proteoglycan receptors.Semantic proximity Read ↗

Selection for a CEACAM Receptor-Specific Binding Phenotype during Neisseria gonorrhoeae Infection of the Human Genital TractSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.