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Article

Genetic and environmental effects on complex traits in mice.

Genetics - 1 Oct 2006

Valdar William, Solberg Leah C, Gauguier Dominique, Cookson William O, Rawlins J Nicholas P, Mott Richard, Flint Jonathan

Abstract excerpt

The interaction between genotype and environment is recognized as an important source of experimental variation when complex traits are measured in the mouse, but the magnitude of that interaction has not often been measured. From a study of 2448 genetically heterogeneous mice, we report the heritability of 88 complex traits that include models of human disease (asthma, type 2 diabetes mellitus, obesity, and...

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Identifiers

PMID: 16888333
DOI: 10.1534/genetics.106.060004
PMCID: PMC1602068

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