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Article

Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women.

Annals of the rheumatic diseases - 1 Sept 2006

Criswell L A, Saag K G, Mikuls T R, Cerhan J R, Merlino L A, Lum R F, Pfeiffer K A, Woehl B, Seldin M F

Abstract excerpt

OBJECTIVE: To determine whether the impact of tobacco exposure on rheumatoid arthritis (RA) risk is influenced by polymorphisms at the HLA-DRB1 and glutathione S-transferase M1 (GSTM1) loci. METHODS: Subjects were participants from a case-control study nested within the Iowa Women's Health Study, a population based, prospective cohort study of postmenopausal women. Incident RA cases (n = 115) were identified and...

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Share to HLA-DR Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arthritis, Rheumatoid

Share to Epidemiologic Methods

Share to Glutathione Transferase

Share to HLA-DRB1 Chains

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Source

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Identifiers

PMID: 16887863
DOI: 10.1136/ard.2005.049676
PMCID: PMC1798304

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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