Article
Potassium channel gene mutations rarely cause atrial fibrillation.
BMC medical genetics - 3 Aug 2006
Ellinor Patrick T, Petrov-Kondratov Vadim I, Zakharova Elena, Nam Edwin G, MacRae Calum A
Abstract excerpt
BACKGROUND: Mutations in several potassium channel subunits have been associated with rare forms of atrial fibrillation. In order to explore the role of potassium channels in inherited typical forms of the arrhythmia, we have screened a cohort of patients from a referral clinic for mutations in the channel subunit genes implicated in the arrhythmia. We sought to determine if mutations in KCNJ2 and KCNE1-5 are a...
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