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Article

Divergent Routes to Oral Cancer

1 Aug 2006

Abstract excerpt

Most head and neck squamous cell carcinoma (HNSCC) patients present with late-stage cancers, which are difficult to treat. Therefore, early diagnosis of high-risk premalignant lesions and incipient cancers is important. HNSCC is currently perceived as a single progression mechanism, resulting in immortal invasive cancers. However, we have found that approximately 40% of primary oral SCCs are mortal in culture,...

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PMID: 16885335
DOI: 10.1158/0008-5472.can-06-0186

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