Article
XbaI-RFLP of the APOB gene in a sample group from southern Italy.
Gene geography : a computerized bulletin on human gene frequencies - 1 Jan 2000
De Benedictis G, Rose G, Leone O, Passarino G, Mazzei R L, Crescibene L, Brancati C
Abstract excerpt
The XbaI Restriction Fragment Length Polymorphism (RFLP) of the APOB gene at codon 2488 was investigated in a sample group from Southern Italy (165 subjects), taken from a population characterized by a low average level of cholesterolemia. The X2 allele (presence of XbaI cutting site), that in several groups was found to be associated with increased cholesterolemia, showed in Southern Italians a frequency of 39%...
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