Article
XbaI polymorphism of the apolipoprotein B gene influences plasma lipid response to diet intervention.
Clinical genetics - 1 May 1990
Tikkanen M J, Xu C F, Hämäläinen T, Talmud P, Sarna S, Huttunen J K, Pietinen P, Humphries S
Abstract excerpt
Fresh blood samples were collected from 103 North Karelians who had in 1981-84 participated in dietary intervention studies and analysis of the XbaI restriction fragment length polymorphism (RFLP) of apolipoprotein B (apoB) was carried out. Reanalysis of the original plasma lipid and apolipoprotein data indicated that while baseline concentrations did not differ significantly between genotypes, the response to a...
Topics
- Adult
- Alleles
- Apolipoproteins B
- Cholesterol
- Cholesterol, HDL
- Cholesterol, LDL
- Coronary Disease
- Female
- Finland
- Genotype
- Humans
- Male
