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Article

Association of Gag cleavage sites to protease mutations and to virological response in HIV-1 treated patients.

The Journal of infection - 1 Apr 2007

Malet Isabelle, Roquebert Bénédicte, Dalban Cécile, Wirden Marc, Amellal Bahia, Agher Rachid, Simon Anne, Katlama Christine, Costagliola Dominique, Calvez Vincent, Marcelin Anne-Geneviève

Abstract excerpt

OBJECTIVES: The sequence variability in the protease and in the 5 Gag cleavage sites (CS) were explored to look for eventual associations between the mutations. Moreover, we have evaluated associations between the Gag region sequence and the virological response to Protease Inhibitors (PI). METHODS: The protease and the 5 Gag CS sequences from 98 PI-experienced patients were sequenced and compared to the HXB2...

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Share to Anti-HIV Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16875739
DOI: 10.1016/j.jinf.2006.06.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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