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Article

The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women.

BMC medical genetics - 31 Jul 2006

Evans David, Beil Frank U

Abstract excerpt

BACKGROUND: Common genetic variants in the PCSK9 gene have been reported to be associated with both elevated and exceptionally low LDL levels. The association of a common haplotype, encompassing the E670G single nucleotide polymorphism, with LDL levels reported by Chen et al (J Am Coll Cardiol 2005; 45: 1644) was not confirmed by Kotowski et al (Am J Hum Genet 2006; 78:410-422). METHODS: The incidence of the...

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Source

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Identifiers

PMID: 16875509
DOI: 10.1186/1471-2350-7-66
PMCID: PMC1562364

Genes

PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women.PMID 16875509Read ↗

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