Article
Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntington's disease.
Histology and histopathology - 1 Nov 2006
Pérez-Navarro E, Canals J M, Ginés S, Alberch J
Abstract excerpt
Neurodegenerative disorders affecting the central nervous system, such as Alzheimer's disease, Parkinson's disease, Huntington's chorea (HD) and amyotrophic lateral sclerosis are characterized by the loss of selected neuronal populations. Another striking feature shared by these diseases is the deposition of proteinaceous inclusion bodies in the brain, which may be intracytoplasmatic or intranuclear, or even...
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