Article
Inherited Variation in Cytokine, Acute Phase Response, and Calcium Metabolism Genes Affects Susceptibility to Infective Endocarditis.
Mediators of inflammation - 1 Jan 2017
Ponasenko Anastasia V, Kutikhin Anton G, Khutornaya Maria V, Rutkovskaya Natalia V, Kondyukova Natalia V, Odarenko Yuri N, Kazachek Yana V, Tsepokina Anna V, Barbarash Leonid S, Yuzhalin Arseniy E
Abstract excerpt
Infective endocarditis (IE) is a septic inflammation of the endocardium. Recognition of microbial patterns, cytokine and acute phase responses, hemostasis features, and alterations in plasma lipid and calcium profile all have been reported to affect pathogenesis and clinical course of IE. Having recruited 123 patients with IE and 300 age-, sex-, and ethnicity-matched healthy blood donors, we profiled their...
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