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Article

Identification of a potential proinflammatory genetic profile influencing carotid plaque vulnerability.

Journal of vascular surgery - 1 Feb 2015

Biscetti Federico, Straface Giuseppe, Bertoletti Giovanni, Vincenzoni Claudio, Snider Francesco, Arena Vincenzo, Landolfi Raffaele, Flex Andrea

Abstract excerpt

OBJECTIVE: Atherosclerosis and vascular remodeling after injury are driven by inflammation and mononuclear cell infiltration. Unstable atherosclerotic plaques are characterized by a large necrotic core. In this study we investigated the distribution and interaction between gene polymorphisms encoding proinflammatory molecules in an Italian population with internal carotid artery stenosis (ICAS). We also evaluated...

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Share to Carotid Intima-Media Thickness
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25441669
DOI: 10.1016/j.jvs.2014.08.113

Genes

CCL2
CCL3
ICAM1
SELE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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