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Article

Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene.

Blood - 1 Nov 2006

Lemmerhirt Heidi L, Shavit Jordan A, Levy Gallia G, Cole Suzanne M, Long Jeffrey C, Ginsburg David

Abstract excerpt

Both genetic and environmental influences contribute to the wide variation in plasma von Willebrand factor (VWF) levels observed in humans. Inbred mouse strains also have highly variable plasma VWF levels, providing a convenient model in which to study genetic modifiers of VWF. Previously, we identified a major modifier of VWF levels in the mouse (Mvwf1) as a regulatory mutation in murine Galgt2. We now report...

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Source

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Identifiers

PMID: 16873672
DOI: 10.1182/blood-2006-04-014688
PMCID: PMC1895519

Genes

VWF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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