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Article

A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.

Proceedings of the National Academy of Sciences of the United States of America - 24 Dec 1996

Mohlke K L, Nichols W C, Westrick R J, Novak E K, Cooney K A, Swank R T, Ginsburg D

Abstract excerpt

Type 1 von Willebrand disease (VWD), characterized by reduced levels of plasma von Willebrand factor (VWF), is the most common inherited bleeding disorder in humans. Penetrance of VWD is incomplete, and expression of the bleeding phenotype is highly variable. In addition, plasma VWF levels vary widely among normal individuals. To identify genes that influence VWF level, we analyzed a genetic cross between RIIIS/J...

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Source

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Identifiers

PMID: 8986815
DOI: 10.1073/pnas.93.26.15352
PMCID: PMC26408

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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