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Article

Lack of association of the PTPN22 gene polymorphism R620W with systemic sclerosis.

Clinical and experimental rheumatology - 1 Jan 2000

Balada E, Simeón-Aznar C P, Serrano-Acedo S, Martínez-Lostao L, Selva-O'Callaghan A, Fonollosa-Pla V, Vilardell-Tarrés M

Abstract excerpt

OBJECTIVE: It has recently been reported that some autoimmune diseases seem to be associated with a functional polymorphism in PTPN22, a gene which encodes a phosphatase known to be important in T-cell signaling. The aim of our study was to check for the prevalence of the PTPN22 R620W polymorphism in patients with systemic sclerosis. METHODS: DNA samples from 54 systemic sclerosis patients and 55 healthy controls...

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Share to Antibodies, Antinuclear
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Topoisomerases, Type I

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Share to Polymorphism, Restriction Fragment Length

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Protein Tyrosine Phosphatases

Share to Scleroderma, Systemic

Source

Identifiers

PMID: 16870103

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Lack of association of the PTPN22 gene polymorphism R620W with systemic sclerosis.PMID 16870103Read ↗

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