Article
Cancer targets in the Ras pathway.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2005
Rodriguez-Viciana P, Tetsu O, Oda K, Okada J, Rauen K, McCormick F
Abstract excerpt
Ras proteins play a direct causal role in human cancer and in other diseases. Mutant H-Ras, N-Ras, and K-Ras occur in varying frequencies in different tumor types, for reasons that are not known. Other members of the Ras superfamily may also contribute to cancer. Mutations also occur in downstrea...
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