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Article

Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation.

Neuropathology and applied neurobiology - 1 Aug 2006

Sundlisaeter E, Wang J, Sakariassen P Ø, Marie M, Mathisen J R, Karlsen B O, Prestegarden L, Skaftnesmo K O, Bjerkvig R, Enger P Ø

Abstract excerpt

Tumour spheroids initiated from glioma biopsy specimens provide a valuable three-dimensional cell culture system that share several biological features of malignant brain tumours in situ. Upon xenotransplantation in immunodeficient rats, tumours derived from such spheroids exhibit a highly infiltrative growth. Successful cryopreservation of spheroid specimens therefore represents an excellent tool for future...

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PMID: 16866987
DOI: 10.1111/j.1365-2990.2006.00744.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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