Article
The association of CYP2D6 *10 polymorphism with breast cancer risk and clinico-pathologic characteristics in Chinese women.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2006
Li Hongxia, Feng Liya, Xu Ye, Yao Lihua, Ouyang Tao, Li Jinfeng, Wang Tianfeng, Fan Zhaoqing, Lin Benyao, Li Jiyou, Xie Yuntao
Abstract excerpt
A relatively little is known of whether CYP2D6 *10 (188 C to T) polymorphism mediates susceptibility to breast cancer. In this study the CYP2D6 *10 polymorphism was detected in Chinese women (286 breast cancer patients and 305 healthy women) by a PCR-RFLP assay. We found that women with the 188T/T genotype displayed a slightly increased risk for breast cancer as compared with those with the 188C/C genotype (OR...
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