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Article

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Oct 2006

Navarro Susana, Meza Nestor W, Quintana-Bustamante Oscar, Casado José A, Jacome Ariana, McAllister Kimberly, Puerto Silvia, Surrallés Jordi, Segovia José C, Bueren Juan A

Abstract excerpt

We have investigated the hematopoietic phenotype of mice with a hypomorphic mutation in the Brca2/Fancd1 gene (Brca2(Delta27/Delta27) mutation). In contrast to observations made in other Fanconi anemia (FA) mouse models, low numbers of hematopoietic colony-forming cells (CFCs) were noted in Brca2...

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Identifiers

PMID: 16859999
DOI: 10.1016/j.ymthe.2006.05.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16859999-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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