Article
Cell elongation and cell death of helicobacter pylori is modulated by the disruption of cdrA (cell division-related gene A).
Microbiology and immunology - 1 Jan 2006
Takeuchi Hiroaki, Nakazawa Teruko, Okamoto Takeshi, Shirai Mutsunori, Kimoto Mitsuo, Nishioka Mitsuaki, Con Sergio A, Morimoto Norihito, Sugiura Tetsuro
Abstract excerpt
The cell division-related gene A (cdrA) of Helicobacter pylori is dispensable in vivo and unique in having a repressive role on cell division and long-term survival. To clarify its role, comparisons of the wildtype HPK5 and isogenic cdrA-disrupted mutant HPKT510 were examined by ultrastructural morphology, PBP profiles, and susceptibility to beta-lactam antibiotics during long-term cultivation. Ultrastructural...
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