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Article

Human foetal osteoblastic cell response to polymer-demixed nanotopographic interfaces.

Journal of the Royal Society, Interface - 22 Mar 2005

Lim Jung Yul, Hansen Joshua C, Siedlecki Christopher A, Runt James, Donahue Henry J

Abstract excerpt

Nanoscale cell-substratum interactions are of significant interest in various biomedical applications. We investigated human foetal osteoblastic cell response to randomly distributed nanoisland topography with varying heights (11, 38 and 85 nm) produced by a polystyrene (PS)/polybromostyrene polymer-demixing technique. Cells displayed island-conforming lamellipodia spreading, and filopodia projections appeared to...

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Identifiers

PMID: 16849169
DOI: 10.1098/rsif.2004.0019
PMCID: PMC1578253

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Source receipt: pubmed, retrieved 7 Sept 2026.

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