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Article

Dual-regulated expression of C/EBP- and BMP-2 enables differential differentiation of C2C12 cells into adipocytes and osteoblasts

2 Jan 2004

Abstract excerpt

CCAAT/enhancer-binding proteins (C/EBPs) as well as bone morphogenic proteins (BMPs) play essential roles in mammalian cell differentiation in shaping adipogenic and osteoblastic lineages in particular. Recent evidence suggested that adipocytes and osteoblasts share a common mesenchymal precursor cell phenotype. Yet, the molecular details underlying the decision of adipocyte versus osteoblast differentiation as...

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PMID: 14704358
DOI: 10.1093/nar/gnh001

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Source receipt: pubmed, retrieved 7 Sept 2026.

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