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Cell‐free fetal DNA: the new tool in fetal medicine

9 Dec 2014

Abstract excerpt

Since the discovery of cell-free fetal DNA (cffDNA) in maternal plasma in 19971 there has been rapid progress in harnessing this as a source of fetal genetic material for prenatal diagnosis. The majority of cell-free DNA (cfDNA) is maternal in origin2, with the fetal proportion emanating from the placenta3, detectable in the maternal circulation from around 5 weeks' gestation2 and constituting around only 10% of...

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PMID: 25483938
DOI: 10.1002/uog.14746

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