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Article

KLF8 transcription factor participates in oncogenic transformation.

Oncogene - 18 Jan 2007

Wang X, Zhao J

Abstract excerpt

Kruppel-like factor 8 (KLF8) is a member of the family of KLF transcription factors. Several KLF members have been shown to play a role in oncogenesis. We have previously demonstrated that KLF8 mediates cell cycle progression downstream of focal adhesion kinase (FAK) by upregulating cyclin D1. FAK plays a critical role in transformation and tumorigenesis and is aberrantly upregulated in many types of human...

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Source

Identifiers

PMID: 16832343
DOI: 10.1038/sj.onc.1209796

Genes

KLF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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