Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

At risk for Huntington disease: The PHAROS (Prospective Huntington At Risk Observational Study) cohort enrolled.

Archives of neurology - 1 Jul 2006

Abstract excerpt

OBJECTIVE: To identify the emerging clinical precursors that indicate the early onset of Huntington disease (HD) in a reliable and gene-specific manner. This information is critical for the development of therapeutic trials aimed at postponing clinical onset in HD gene carriers. METHODS: Between July 1999 and January 2004, 1001 adults at 50-50 risk for HD agreed to provide longitudinal clinical data and a blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Age of Onset
Share to Huntingtin Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Huntington Disease

Share to Longitudinal Studies

Share to Nerve Tissue Proteins

Share to Nuclear Proteins

Share to Sex Distribution

Source

Identifiers

PMID: 16831969
DOI: 10.1001/archneur.63.7.991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

At risk for Huntington disease: The PHAROS (Prospective Huntington At Risk Observational Study) cohort enrolled.PMID 16831969Read ↗

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials.Semantic proximity Read ↗

Characterization of a large group of individuals with huntington disease and their relatives enrolled in the COHORT study.Semantic proximity Read ↗

Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS.Semantic proximity Read ↗

Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS): a cross-sectional analysisSemantic proximity Read ↗

The clinical and genetic features of Huntington disease.Semantic proximity Read ↗

Huntington’s Disease Integrated Staging System (HD-ISS): A Novel Evidence-Based Classification System For StagingSemantic proximity Read ↗

Future directions in research with presymptomatic individuals carrying the gene for Huntington's disease.Semantic proximity Read ↗

Huntington Disease: Genetics, Prevention, and Therapy Approaches.Semantic proximity Read ↗

Genetic epidemiological characteristics of a Hungarian subpopulation of patients with Huntington’s DiseaseSemantic proximity Read ↗

A biological classification of Huntington's disease: the Integrated Staging System.Semantic proximity Read ↗

Huntington’s Disease Pathogenesis: Two Sequential ComponentsSemantic proximity Read ↗

Clinical and genetic characteristics of late-onset Huntington's disease in a large European cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.