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Article

The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism.

Genome research - 1 Jun 2012

Salm Maximilian P A, Horswell Stuart D, Hutchison Claire E, Speedy Helen E, Yang Xia, Liang Liming, Schadt Eric E, Cookson William O, Wierzbicki Anthony S, Naoumova Rossi P, Shoulders Carol C

Abstract excerpt

Genomic inversions are an increasingly recognized source of genetic variation. However, a lack of reliable high-throughput genotyping assays for these structures has precluded a full understanding of an inversion's phylogenetic, phenotypic, and population genetic properties. We characterize these properties for one of the largest polymorphic inversions in man (the ∼4.5-Mb 8p23.1 inversion), a structure that...

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Identifiers

PMID: 22399572
DOI: 10.1101/gr.126037.111
PMCID: PMC3371712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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