Article
Sporadic aneuploidy in PHA-stimulated lymphocytes of Turner's syndrome patients.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology - 1 Jan 2006
Reish Orit, Brosh Nirit, Gobazov Rima, Rosenblat Malka, Libman Vitalia, Mashevich Maya
Abstract excerpt
In line with the view that aneuploidy destabilizes the karyotype, initiating an autocatalytic process that gives rise to further loss and/or gain of chromosomes, we examined whether a constitutional aneuploidy such as monosomy for one chromosome is associated with sporadic loss and/or gain of other chromosomes. We used PHA-stimulated lymphocytes from eight women with Turner's syndrome (six displayed X chromosome...
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