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Article

DNA polymorphism and linkage disequilibrium within the apolipoprotein CII locus on human chromosome 19.

Human heredity - 1 Jan 1991

MacKenzie A E, MacLeod H L, Leblond S C, Monteith N, Lahey D, Korneluk R G

Abstract excerpt

The gene for human apolipoprotein CII (APOCII) is located on the proximal long arm of chromosome 19. It has been established as a closely linked marker for myotonic dystrophy (DM), the most common form of adult muscular dystrophy. In the present linkage study, we have analysed 6 APOCII RFLPs in 213 haplotypes: TaqI, 3.8/3.5 kb; BgII, 12.0/9.0 kb; BanI, 2.5/1.6 kb; BamHI, 6.0/4.9 kb; NcoI, 14.5/11.5 kb, and AvaII,...

Topics

Alleles
Apolipoprotein C-II
Apolipoproteins C
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 19
DNA
Humans
Linkage Disequilibrium
Molecular Sequence Data
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1682238
DOI: 10.1159/000153999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1682238-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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