Article
Linkage disequilibrium of three polymorphic RFLP markers in the apolipoprotein AI-CIII gene cluster on chromosome 11.
Human genetics - 1 Mar 1993
Marasco O, Melina F, Mele E, Quaresima B, Zingone A, Focarelli E, Picciotti E, Martelli M L, Fotino L, Vigna M F
Abstract excerpt
We analysed the allelic and genotypic frequencies of three restriction fragment length polymorphisms in the region of chromosome 11 encoding apolipoprotein AI and CIII genes in a free-living population from South Italy (Calabria). These markers are located at -2500 and -78 bp from the transcripti...
Topics
- Adult
- Aged
- Alleles
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins
- Apolipoproteins C
- Base Sequence
- Blotting, Southern
- Chi-Square Distribution
- Chromosomes, Human, Pair 11
- DNA
- Female
- Gene Frequency
- Genetic Markers
- Haplotypes
- Humans
- Hypercholesterolemia