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Article

The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion.

Lipids in health and disease - 5 Jul 2006

Wung Shu-Fen, Kulkarni Medha V, Pullinger Clive R, Malloy Mary J, Kane John P, Aouizerat Bradley E

Abstract excerpt

BACKGROUND: Lipoprotein Lipase (LPL), a key enzyme in lipid metabolism, catalyzes the hydrolysis of triglycerides (TG) from TG-rich lipoproteins, and serves a bridging function that enhances the cellular uptake of lipoproteins. Abnormalities in LPL function are associated with pathophysiological conditions, including familial combined hyperlipidemia (FCH). Whereas two LPL susceptibility alleles were found to...

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Identifiers

PMID: 16822320
DOI: 10.1186/1476-511X-5-19
PMCID: PMC1538992

Genes

LPL

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion.PMID 16822320Read ↗

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