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Article

The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jun 1994

Nevin D N, Brunzell J D, Deeb S S

Abstract excerpt

Familial combined hyperlipidemia (FCHL) is an oligogenic disorder, with family members having elevated apolipoprotein B-100 levels and either elevated plasma cholesterol or triglyceride levels or both. Obligate heterozygous parents of children with lipoprotein lipase (LPL) deficiency express a mild FCHL phenotype. Of patients with FCHL, 36% have diminished postheparin LPL activity and mass values that are...

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Source

Identifiers

PMID: 8199176
DOI: 10.1161/01.atv.14.6.869

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity.PMID 8199176Read ↗

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Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia.Semantic proximity Read ↗

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Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene.Semantic proximity Read ↗

Molecular analysis of three known and one novel LPL variants in patients with type I hyperlipoproteinemia.Semantic proximity Read ↗

A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity.Semantic proximity Read ↗

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Association between lipoprotein lipase (LPL) gene and blood lipids: a common variant for a common trait?Semantic proximity Read ↗

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