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Article

Physiochemical characterization of the Alzheimer's disease-related peptides A beta 1-42Arctic and A beta 1-42wt.

The FEBS journal - 1 Jun 2006

Johansson Ann-Sofi, Berglind-Dehlin Fredrik, Karlsson Göran, Edwards Katarina, Gellerfors Pär, Lannfelt Lars

Abstract excerpt

The amyloid beta peptide (A beta) is crucial for the pathogenesis of Alzheimer's disease. Aggregation of monomeric A beta into insoluble amyloid fibrils proceeds through several soluble A beta intermediates, including protofibrils, which are believed to be central in the disease process. The main reason for this is their implication in familial Alzheimer's disease with the Arctic amyloid precursor protein...

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PMID: 16817891
DOI: 10.1111/j.1742-4658.2006.05263.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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